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KMID : 0370920120290020132
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Yeungnam Univercity Journal of Medicine
2012 Volume.29 No. 2 p.132 ~ p.135
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A Case of Adrenocortical Carcinoma Secreting Cortisol and Aldosterone
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Ha Ji-Yoon
Kim Min-Kyung
Cha Yoon-Jin
Kim Seung-Kyu
Yun Gi-Young
Lee Kwang-Won
Park Joon-Seong
Cho Eun-Suk
Ahn Chul-Woo
Park Jong-Suk
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Abstract
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Adrenocortical carcinomas are rare and frequently aggressive tumors that may be functional (hormone-secreting) and may cause Cushing’s syndrome or virilization, or non-functional and manifest as an abdominal mass. This paper reports the case of a 77-year-old woman with cortisol- and aldosterone-secreting adrenal carcinoma. The patient complained of general weakness, a moon face, and weight gain. She also had hypokalemia and hypertension. Her endocrinological data showed excessive aldosterone production and non-suppressible cortisol production in a low-dose dexamethasone suppresion test. Her abdominal CT showed a right adrenal mass. She underwent right adrenalectomy, and her histology revealed the presence of adrenocortical carcinoma. After adrenalectomy, her hypokalemia returned to normal and she is being treated with hydrocortisone.
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KEYWORD
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Adrenocortical carcinoma, Aldosterone, Cortisol, Cushing’s syndrome, Primary aldosteronism
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